abstract：:Systemic acquired resistance (SAR) to Uromyces pisi in pea was studied by using a proteomic approach. Two-dimensional electrophoresis (2-DE) was used in order to compare the leaf proteome of two pea genotypes displaying different phenotypes (susceptible and partial resistance to the fungus), and in response to parasit...

journal_title：Journal of proteomics

authors： Barilli E,Rubiales D,Castillejo MÁ

更新日期：2012-09-18 00:00:00

abstract：:A phaC knockout mutant from Bacillus thuringiensis (Bt) strain BMB171, named BMB171/PHB(-1), was constructed. A physiological and metabolic investigation and a proteomic analysis were conducted for both ΔphaC mutant and its parent strain. Grown in peptone medium with 5 gram glucose per liter as sole carbon source, BMB...

journal_title：Journal of proteomics

authors： Chen D,Xu D,Li M,He J,Gong Y,Wu D,Sun M,Yu Z

更新日期：2012-09-18 00:00:00

abstract：:Multidrug resistance (MDR), a ubiquitous phenomenon conserved from bacteria to humans, causes serious problems in the treatment of human cancers and infections of bacterial and fungal origin. The development of MDR in yeast is frequently associated with gain-of-function mutations in the Zn(2)Cys(6) transcription facto...

journal_title：Journal of proteomics

authors： Hodurova Z,Ferreira L,Sánchez-Juanes F,Dominguez A,Gbelska Y

更新日期：2012-09-18 00:00:00

abstract：:Royal jelly (RJ) is a secretory protein from the hypopharyngeal glands of nurse honeybee workers, which contains a variety of proteins of which major royal jelly proteins (MRJPs) are some of the most important. It plays important roles both for honeybee and human. Each family of MRJP 1-5 displays a string of modified ...

journal_title：Journal of proteomics

authors： Zhang L,Fang Y,Li R,Feng M,Han B,Zhou T,Li J

更新日期：2012-09-18 00:00:00

abstract：:One of the important challenges for MALDI imaging mass spectrometry (MALDI-IMS) is the unambiguous identification of measured analytes. One way to do this is to match tryptic peptide MALDI-IMS m/z values with LC-MS/MS identified m/z values. Matching using current MALDI-TOF/TOF MS instruments is difficult due to the va...

journal_title：Journal of proteomics

authors： Gustafsson JOR,Eddes JS,Meding S,Koudelka T,Oehler MK,McColl SR,Hoffmann P

更新日期：2012-08-30 00:00:00

abstract：:Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for the localization of molecules in biological tissues. In drug discovery and development, understanding the distribution of both drug and its metabolites is of critical importance. Traditional methods suffer from a lack of spatia...

journal_title：Journal of proteomics

authors： Prideaux B,Stoeckli M

更新日期：2012-08-30 00:00:00

abstract：:Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface of a wide variety of samples, allowing the multiplex measurement of both abundance and distribution of small molecules, lipids, peptides and proteins. As the technology has been refined an increasing number of ionization methods ...

journal_title：Journal of proteomics

authors： Goodwin RJA

更新日期：2012-08-30 00:00:00

abstract：:The present study describes the response of a bacterial strain, isolated from a hot spring in an area with the highest levels of natural radiation, under radium ((226)Ra) stress. The bacterium has been characterized as a novel and efficient radium biosorbent and identified as a variant of Serratia marcescens by bioche...

journal_title：Journal of proteomics

authors： Zakeri F,Sadeghizadeh M,Kardan MR,Shahbani Zahiri H,Ahmadian G,Masoumi F,Sharafi H,Rigi G,Vali H,Akbari Noghabi K

更新日期：2012-08-03 00:00:00

abstract：:One of the deadly hallmarks of cancer is its ability to prosper within the constraints of the host immune system. Recent advances in immunoproteomics and high-throughput technologies have lead to profiling of the antibody repertoire in cancer patients. This in turn has lead to the identification of tumour associated a...

journal_title：Journal of proteomics

authors： Murphy MA,O'Leary JJ,Cahill DJ

更新日期：2012-08-03 00:00:00

abstract：:Xenotropic murine leukemia virus-related virus (XMRV) is a virus generated under artificial conditions by the recombination of 2 murine leukemia virus (MLV) proviruses, PreXMRV-1 and PreXMRV-2, during the in vivo passage of human prostate cancer cells in athymic nude mice. The molecular etiology of XMRV infection has ...

journal_title：Journal of proteomics

authors： Matsunaga S,Sawasaki T,Ode H,Morishita R,Furukawa A,Sakuma R,Sugiura W,Sato H,Katahira M,Takaori-Kondo A,Yamamoto N,Ryo A

更新日期：2012-08-03 00:00:00

abstract：:The regulation of mitochondrial function is essential for cardiomyocyte adaptation to cellular stress. While it has long been understood that phosphorylation regulates flux through metabolic pathways, novel phosphorylation sites are continually being discovered in all functionally distinct areas of the mitochondrial p...

journal_title：Journal of proteomics

authors： Lam MP,Scruggs SB,Kim TY,Zong C,Lau E,Wang D,Ryan CM,Faull KF,Ping P

更新日期：2012-08-03 00:00:00

abstract：:Meat tenderness prediction is a challenging task, especially in Maremmana, an Italian autochtonous and highly appreciated beef breed. In the present study we reported an integrated proteomics, phosphoproteomics and metabolomics overview of meat tenderness in longissimus dorsi from 15 male Maremmana individuals, throug...

journal_title：Journal of proteomics

authors： D'Alessandro A,Rinalducci S,Marrocco C,Zolla V,Napolitano F,Zolla L

更新日期：2012-07-19 00:00:00

abstract：:Ticks are mostly obligatory blood feeding ectoparasites that have an impact on human and animal health. In addition to direct damage due to feeding, some tick species serve as the vectors for the causative agents of several diseases, such as the spirochetes of the genus Borrelia causing Lyme disease, the virus of tick...

journal_title：Journal of proteomics

authors： Chmelar J,Calvo E,Pedra JH,Francischetti IM,Kotsyfakis M

更新日期：2012-07-16 00:00:00

abstract：:Human populations are constantly plagued by hematophagous insects' bites, in particular the triatomine insects that are vectors of the Trypanosoma cruzi agent in Chagas disease. The pharmacologically-active molecules present in the salivary glands of hematophagous insects are injected into the human skin to initiate a...

journal_title：Journal of proteomics

authors： de Araújo CN,Bussacos AC,Sousa AO,Hecht MM,Teixeira AR

更新日期：2012-07-16 00:00:00

abstract：:Sorghum bicolor, a drought tolerant cereal crop, is not only an important food source in the semi arid/arid regions but also a potential model for studying and gaining a better understanding of the molecular mechanisms of drought and salt stress tolerance in cereals. In this study, seeds of a sweet sorghum variety, MN...

journal_title：Journal of proteomics

authors： Ngara R,Ndimba R,Borch-Jensen J,Jensen ON,Ndimba B

更新日期：2012-07-16 00:00:00

abstract：:Nitric oxide is a pain signaling molecule and exerts its influence through two primary pathways: by stimulation of soluble guanylylcyclase and by direct S-nitrosylation (SNO) of target proteins. We assessed in the spinal cord the SNO-proteome with two methods, two-dimensional S-nitrosothiol difference gel electrophore...

journal_title：Journal of proteomics

authors： Scheving R,Wittig I,Heide H,Albuquerque B,Steger M,Brandt U,Tegeder I

更新日期：2012-07-16 00:00:00

abstract：:Porosomes are the universal secretory portals at the cell plasma membrane, where membrane-bound secretory vesicles transiently dock and fuse to expel intravesicular contents to the outside during cell secretion. In the past decade, the neuronal porosome complex, a 10-15nm cup-shaped lipoprotein structure has been isol...

journal_title：Journal of proteomics

authors： Lee JS,Jeremic A,Shin L,Cho WJ,Chen X,Jena BP

更新日期：2012-07-16 00:00:00

abstract：:Many powerful analytical techniques for investigation of nucleic acids exist in the average modern molecular biology lab. The current review will focus on questions in RNA biology that have been answered by the use of mass spectrometry, which means that new biological information is the purpose and outcome of most of ...

journal_title：Journal of proteomics

authors： Giessing AM,Kirpekar F

更新日期：2012-06-27 00:00:00

abstract：:The silkworm Bombyx mori is of great economic value. The B. mori nuclear polyhedrosis virus (BmNPV) is one of the most common and severe pathogens for silkworm. Although certain immune mechanisms exist in silkworms, most silkworms are still susceptible to BmNPV infection. Interestingly, BmNPV infection resistance in s...

journal_title：Journal of proteomics

authors： Qin L,Xia H,Shi H,Zhou Y,Chen L,Yao Q,Liu X,Feng F,Yuan Y,Chen K

更新日期：2012-06-27 00:00:00

abstract：:The soy-derived phytoestrogen genistein (GEN) has received attention for its potential benefits on the cardiovascular system by providing direct protection to cardiomyocytes against pathophysiological stresses. Here, we employed a proteomic approach to study the concentration-dependent effects of GEN treatments on car...

journal_title：Journal of proteomics

authors： Sun Z,Biela LM,Hamilton KL,Reardon KF

更新日期：2012-06-27 00:00:00

abstract：:Transfer ribonucleic acid (tRNA) is the non-coding RNA that links the processes of gene transcription with protein translation. While tRNAs have, individually, been studied for many years, few approaches exist for the global identification of tRNAs at the RNA and posttranscriptional RNA levels. Previously our lab intr...

journal_title：Journal of proteomics

authors： Wetzel C,Limbach PA

更新日期：2012-06-27 00:00:00

abstract：:Histone proteins contribute to the maintenance and regulation of the dynamic chromatin structure, to gene activation, DNA repair and many other processes in the cell nucleus. Site-specific reversible and irreversible post-translational modifications of histone proteins mediate biological functions, including recruitme...

journal_title：Journal of proteomics

authors： Sidoli S,Cheng L,Jensen ON

更新日期：2012-06-27 00:00:00

abstract：:Dystrobrevin is a dystrophin-related component of the dystrophin-associated protein complex (DAPC). Using alpha-dystrobrevin as indicator, we aimed to elucidate the interaction network of the DAPC with other proteins during apoptosis of promyelocytic HL-60 cells. The precise role(s) of DBs are not known, but we and ot...

journal_title：Journal of proteomics

authors： Navakauskienė R,Treigytė G,Borutinskaitė VV,Matuzevičius D,Navakauskas D,Magnusson KE

更新日期：2012-06-18 00:00:00

abstract：:Both transmission electron microscopy (TEM) and fluorescence spectrometry were used to reveal the characteristics of both subunit disassociation and recombination in apo-pig pancreas ferritin (apoPPF) in an alkaline medium ranging reversibly from pH 7.0 to 13.0. The experimental results indicated that apoPPF could be ...

journal_title：Journal of proteomics

authors： Ji XT,Huang L,Huang HQ

更新日期：2012-06-18 00:00:00

abstract：:Post-weaning multi-systemic wasting syndrome (PMWS), which is primarily caused by porcine circovirus type 2 (PCV2), is an emerging swine immunosuppressive disease. To characterize the interaction between target immune cells and PCV2, the differential proteomes of porcine alveolar macrophages, with and without PCV2 inf...

journal_title：Journal of proteomics

authors： Cheng S,Zhang M,Li W,Wang Y,Liu Y,He Q

更新日期：2012-06-18 00:00:00

abstract：:Corynebacterium glutamicum can utilize various monocyclic aromatic carbon sources, including protocatechuate, which is catabolized via the β-ketoadipate pathway. In order to obtain a global survey of occurring physiological adaptations on the proteome level, cytoplasmic and membrane fraction from cells grown on protoc...

journal_title：Journal of proteomics

authors： Haussmann U,Poetsch A

更新日期：2012-05-17 00:00:00

abstract：:Compared to radiation-sensitive bacteria, the nucleoids of radiation-resistant Deinococcus species show a higher degree of compaction. Such a condensed nucleoid may contribute to the extreme radiation resistance of Deinococcus by limiting dispersion of radiation-induced DNA fragments. Architectural proteins may play a...

journal_title：Journal of proteomics

authors： Toueille M,Mirabella B,Guérin P,Bouthier de la Tour C,Boisnard S,Nguyen HH,Blanchard L,Servant P,de Groot A,Sommer S,Armengaud J

更新日期：2012-05-17 00:00:00

abstract：:One of the main concerns about genetically modified foods and their potential impacts on human health is that the introduction of a new/ altered gene may putatively alter the expression of others, namely endogenous allergens. We intended to evaluate, and to compare, using quantitative real time RT-PCR technique, the e...

journal_title：Journal of proteomics

authors： Fonseca C,Planchon S,Renaut J,Oliveira MM,Batista R

更新日期：2012-04-03 00:00:00

abstract：:Sheep have a variable ability to resist gastrointestinal nematode infection, but the key factors mediating this response are poorly defined. Here we report the first large-scale application of quantitative proteomic technologies to define proteins that are differentially abundant between sheep selectively bred to have...

journal_title：Journal of proteomics

authors： Nagaraj SH,Harsha HC,Reverter A,Colgrave ML,Sharma R,Andronicos N,Hunt P,Menzies M,Lees MS,Sekhar NR,Pandey A,Ingham A

更新日期：2012-04-03 00:00:00

abstract：:Quantitative proteomic comparisons require a sufficient number of samples to reach an acceptable level of significance. But 2D gel electrophoresis commonly results in incomplete data sets due to spots with missing values reducing thereby the number of parallel measurements for individual proteins. Here we investigated...

journal_title：Journal of proteomics

authors： Zellner M,Graf A,Zehetmayer S,Winkler W,Staes A,Gevaert K,Vandekerckhove J,Marchetti-Deschmann M,Miller I,Bauer P,Allmaier G,Oehler R

更新日期：2012-03-16 00:00:00

abstract：:Chronic Schistosoma mansoni infection can present as a moderate or severe disease, termed intestinal or hepatosplenic schistosomiasis, respectively. Similarly, either moderate splenomegaly or hypersplenomegaly syndrome develops in CBA/J mice by 20weeks of infection and is similar to intestinal or hepatosplenic schisto...

journal_title：Journal of proteomics

authors： Manivannan B,Jordan TW,Secor WE,La Flamme AC

更新日期：2012-03-16 00:00:00

abstract：:Selenium (Se) shows both beneficial and toxic effects on plant growth. Rice (Oryza sativa L.) seedlings cultivated under lower concentrations of sodium selenite showed enhanced growth, whereas higher concentrations of sodium selenite repressed seedling growth. To acquire detailed regulatory mechanisms underlying these...

journal_title：Journal of proteomics

authors： Wang YD,Wang X,Wong YS

更新日期：2012-03-16 00:00:00

abstract：:Salinity is one of the major environmental constraints limiting yield of crop plants in many semi-arid and arid regions around the world. To understand responses in soybean seedling to salt stress at proteomic level, the extracted proteins from seedling leaves of salt-sensitive genotype Jackson and salt-tolerant genot...

journal_title：Journal of proteomics

authors： Ma H,Song L,Shu Y,Wang S,Niu J,Wang Z,Yu T,Gu W,Ma H

更新日期：2012-02-16 00:00:00

abstract：:The membrane glycoprotein CD82 (KAI1) has attracted increasing attention as a suppressor of cell migration, related tumor invasion, as well as metastasis. The glycosylation of CD82 has been shown to be involved in a correlative cell adhesion and motility. However, the N-glycosylation pattern of CD82 has not been descr...

journal_title：Journal of proteomics

authors： Wang H,Zhang W,Zhao J,Zhang L,Liu M,Yan G,Yao J,Yu H,Yang P

更新日期：2012-02-02 00:00:00

abstract：:We have used differential sub-proteomic methodologies to detect Edwardsiella tarda outer membrane (OM) protein expression regulation during interaction with fish and human plasma, which is the critical step of the bacterial invasion internal organs via blood circulation. Seven and nine OM proteins were differentially ...

journal_title：Journal of proteomics

authors： Wang C,Liu Y,Li H,Xu WJ,Zhang H,Peng XX

更新日期：2012-02-02 00:00:00

abstract：:The proteins secreted by prostate cancer cells (PC3(AR)6) were separated by strong anion exchange chromatography, digested with trypsin and analyzed by unbiased liquid chromatography tandem mass spectrometry with an ion trap. The spectra were matched to peptides within proteins using a goodness of fit algorithm that s...

journal_title：Journal of proteomics

authors： Florentinus AK,Bowden P,Sardana G,Diamandis EP,Marshall JG

更新日期：2012-02-02 00:00:00

abstract：:Geobacillus thermodenitrificans NG80-2 is a crude oil-degrading thermophilic bacterium isolated from an oil reservoir in China. In this study, the gene clusters and pathways for the degradation of benzoate (via benzoyl-CoA), phenylacetate (via phenylacetyl-CoA), 4-hydroxyphenylacetate (via 3,4-dihydroxyphenylacetate) ...

journal_title：Journal of proteomics

authors： Li Y,Wu J,Wang W,Ding P,Feng L

更新日期：2012-02-02 00:00:00

abstract：:Understanding the relationship between physical exercise, reactive oxygen species and skeletal muscle modification is important in order to better identify the benefits or the damages that appropriate or inappropriate exercise can induce. Unbalanced ROS levels can lead to oxidation of cellular macromolecules and a maj...

journal_title：Journal of proteomics

authors： Magherini F,Abruzzo PM,Puglia M,Bini L,Gamberi T,Esposito F,Veicsteinas A,Marini M,Fiorillo C,Gulisano M,Modesti A

更新日期：2012-01-04 00:00:00

abstract：:Vav1 is a key molecule in the ATRA-induced acquisition of a mature phenotype by tumoral myeloid precursors. Since ATRA acts throughout events that require extensive changes of nuclear architecture and activity and considering that Vav1 accumulates inside the nuclear compartment of differentiating APL-derived cells, th...

journal_title：Journal of proteomics

authors： Bertagnolo V,Grassilli S,Petretto A,Lambertini E,Astati L,Bruschi M,Brugnoli F,Nika E,Candiano G,Piva R,Capitani S

更新日期：2011-12-21 00:00:00

abstract：:Characterization of the biomolecules involved in molecular processes occurring in biological systems such as the human cell remains central to biology, biotechnology, and medicine. One of the preferred methods of selectively purifying specific classes of biomolecules from complex biological matrices for further charac...

journal_title：Journal of proteomics

authors： Engholm-Keller K,Larsen MR

更新日期：2011-12-21 00:00:00